Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17161709 | 0.86 | NPC1 (0.46) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL17559642 | 0.86 | NPC1 (0.46) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL7469312 | 0.86 | NPC1 (0.49) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL10723226 | 0.86 | NR4A2 (0.58) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL1416482 | 0.86 | NR4A2 (0.58) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL8797872 | 0.86 | NPC1 (0.49) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL8797866 | 0.86 | NPC1 (0.49) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL19578100 | 0.85 | KMT2A (0.45) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL7425740 | 0.84 | CA12 (0.51) | NPC1RAB9AADRA2BADRA2CSLC6A2 | |
| SCHEMBL10532188 | 0.84 | CA12 (0.51) | NPC1RAB9AADRA2BADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183101-C | Derivatives of alpha-amino acid phenyl ester | ��˹��ŵ�� | 2005-01-05 | — | — | CN | disclosed |
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |
| CN-1311770-A | Derivatives of alpha-amino acid phenyl ester | AKZO NOBEL NV (NL) | 2001-09-05 | — | — | CN | disclosed |
| EP-1098871-A1 | $g(a)-AMINO ACID PHENYL ESTER DERIVATIVES | Akzo Nobel N.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005196-A1 | α-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL N.V. (NL) | 2000-02-03 | — | — | WO | disclosed |