Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723226 | 1.00 | NR4A2 (0.58) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL27711514 | 0.91 | NR4A2 (0.51) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL11823514 | 0.88 | ADRA2B (0.56) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL900942 | 0.86 | ADRA2B (0.54) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL17772991 | 0.86 | NR4A2 (0.51) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL8797866 | 0.86 | NPC1 (0.49) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7469312 | 0.86 | NPC1 (0.49) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL8797872 | 0.86 | NPC1 (0.49) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7140937 | 0.86 | NPC1 (0.49) | NR4A2ADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL17931635 | 0.84 | MAOB (0.52) | NR4A2ADRA2BADRA2CSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190021380-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-01-24 | — | — | US | disclosed |
| EP-1721898-B1 | Quinoline and pyridoquinoxaline derivatives as antibacterial agents | UNIV JORDAN (JO) | 2011-03-16 | — | — | EP | disclosed |
| US-RE32534-E | Peptides, process for preparing the same and psychodepressant compositions containing the same | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| EP-0107860-B1 | PEPTIDES, PROCESS FOR PREPARING THE SAME AND PSYCHODEPRESSANT COMPOSITIONS CONTAINING THE SAME | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |
| US-4517180-A | SCHIZOPHRENIA | AMANO PHARMACEUTICAL CO., LTD (JP) | 1985-05-14 | — | — | US | disclosed |
| EP-0107860-A1 | Peptides, process for preparing the same and psychodepressant compositions containing the same | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |