Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521802 | 0.90 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL10252171 | 0.83 | IKBKB (0.45) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL14458021 | 0.81 | SMN1; SMN2 (0.43) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL14458014 | 0.81 | ESR2 (0.51) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL6615105 | 0.81 | GAA (0.45) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL13945018 | 0.81 | GAA (0.45) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL23878342 | 0.75 | TDP1 (0.46) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL22201140 | 0.75 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL22201147 | 0.75 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DHDAC2 | |
| SCHEMBL22201146 | 0.75 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322604-A1 | DELTA 1-PYRROLINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024644-A1 | DELTA 1-PYRROLINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |