Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.66 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400915 | 0.80 | TLR8 (0.56) | TLR8TLR7ADORA2AADORA3ADORA1 | |
| SCHEMBL1527825 | 0.80 | TLR7 (1.00) | TLR8TLR7ADORA2AADORA3ADORA1 | |
| SCHEMBL1527927 | 0.78 | TLR8 (0.72) | TLR8TLR7POLBDCPS | |
| Hydrochloric Acid SCHEMBL5768405 | 0.78 | TLR7 (0.97) | TLR8TLR7ADORA2AADORA3ADORA1 | |
| SCHEMBL1527890 | 0.76 | TLR7 (1.00) | TLR8TLR7POLBADORA2AADORA3 | |
| SCHEMBL1528137 | 0.76 | TLR8 (1.00) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL5767005 | 0.75 | TLR8 (0.97) | TLR8TLR7 | |
| SCHEMBL2808735 | 0.75 | TLR8 (0.72) | TLR8TLR7ADORA2AADORA3ADORA1 | |
| Hydrochloric Acid SCHEMBL2807427 | 0.74 | TLR8 (0.70) | TLR8TLR7DCPS | |
| SCHEMBL482958 | 0.74 | TLR8 (1.00) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100802-B1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLINE-4-AMINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2003-09-24 | — | — | EP | disclosed |