Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141148 | 1.00 | F10 (0.44) | F10MAP4K4DGAT1PDCD1CD274 | |
| SCHEMBL7144367 | 0.89 | F10 (0.47) | F10DGAT1ITGB3ITGA2B | |
| SCHEMBL7144382 | 0.89 | F10 (0.47) | F10DGAT1ITGB3ITGA2B | |
| SCHEMBL4389189 | 0.88 | F10 (0.47) | F10DGAT1 | |
| SCHEMBL7145836 | 0.87 | F10 (0.48) | F10DGAT1 | |
| SCHEMBL7145840 | 0.87 | F10 (0.48) | F10DGAT1 | |
| SCHEMBL4388083 | 0.86 | F10 (0.46) | F10DGAT1 | |
| SCHEMBL4388077 | 0.86 | F10 (0.46) | F10DGAT1 | |
| SCHEMBL7150928 | 0.85 | F10 (0.47) | F10MAP4K4DGAT1 | |
| SCHEMBL1384927 | 0.85 | F10 (0.46) | F10DGAT1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |