Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141598 | 1.00 | LMNA (0.31) | LMNAKMT2ATLR4 | |
| SCHEMBL7136807 | 0.93 | TLR4 (0.34) | LMNAKMT2ATLR4 | |
| SCHEMBL7136812 | 0.93 | TLR4 (0.34) | LMNAKMT2ATLR4 | |
| SCHEMBL7141779 | 0.91 | TLR4 (0.36) | LMNAKMT2ATLR4 | |
| SCHEMBL7141782 | 0.91 | TLR4 (0.36) | LMNAKMT2ATLR4 | |
| SCHEMBL7133789 | 0.90 | TLR4 (0.34) | TLR4 | |
| SCHEMBL7133793 | 0.90 | TLR4 (0.34) | TLR4 | |
| SCHEMBL7177273 | 0.89 | BTN3A1 (0.31) | TLR4 | |
| SCHEMBL7177274 | 0.89 | BTN3A1 (0.31) | TLR4 | |
| SCHEMBL7143293 | 0.84 | TLR4 (0.36) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6511965-B2 | For therapy and prophylaxis of inflammatory disorders, autoimmune diseases or septicemia | SANKYO COMPANY, LIMITED (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1152007-A1 | ETHER TYPE LIPID A1-CARBOXYLIC ACID ANALOGUES | Sankyo Company, Limited (JP) | 2001-11-07 | — | — | EP | disclosed |