Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903603 | 0.94 | KMT2A (0.76) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL8752540 | 0.93 | KMT2A (0.78) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL3369379 | 0.93 | KMT2A (0.78) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL1417537 | 0.85 | CA1 (0.71) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL2240008 | 0.85 | CA1 (0.71) | MAPTLMNAMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL10521332 | 0.82 | KMT2A (0.74) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28109022 | 0.81 | MAPT (0.78) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28754776 | 0.81 | KMT2A (0.73) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28423611 | 0.81 | KMT2A (0.72) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL4953484 | 0.80 | KMT2A (0.76) | MAPTLMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002032864-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-25 | — | — | WO | disclosed |