⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Magnesium SCHEMBL7983993 | 0.97 | — | — | |
| Fluoride Ion SCHEMBL4887924 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9645205 | 0.94 | — | — | |
| SCHEMBL27689204 | 0.82 | — | — | |
| SCHEMBL254444 | 0.78 | CA1 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL1420784 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL11793529 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL1537738 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL6518481 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL21049480 | 0.74 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | SHISEIDO COMPANY LTD. (JP) | 2007-09-27 | — | — | US | claimed |
| EP-1688126-A1 | PARAKERATOSIS INHIBITOR AND EXTERNAL COMPOSITION FOR SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-09 | — | — | EP | claimed |
| JP-63210660-A | — | — | None | — | — | JP | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-8586638-B2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY, LTD (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20120253064-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | SHISEIDO COMPANY, LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2491981-A2 | Parakeratosis inhibitor and external composition for skin | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2491980-A2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120053243-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | SHISEIDO COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | SHISEIDO COMPANY LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1688126-A1 | PARAKERATOSIS INHIBITOR AND EXTERNAL COMPOSITION FOR SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-09 | — | — | EP | disclosed |
| EP-0078545-B1 | IMIDAZOLECARBOXYLIC ACID DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4704391-A | Pyridazinones, and pharmaceutical preparations thereof | CIBA-GEIGY CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4677186-A | AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS | CIBA-GEIGY CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4654340-A | Pyridazinones, pharmaceutical preparations containing these compounds, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1987-03-31 | — | — | US | disclosed |
| US-4629685-A | PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES | CIBA-GEIGY CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |
| US-4624951-A | Substituted pyridazinones, pharmaceutical preparations containing these compounds, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |
| US-4613599-A | Method of treating thrombotic disease with pyridazinones | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| US-4418071-A | Cardiotonic imidazolecarboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0078545-A1 | Imidazolecarboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-11 | — | — | EP | disclosed |