Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifosmin SCHEMBL291309 | 0.97 | ALDH1A1 (0.35) | ALDH1A1GAATSHR | |
| Trifosmin SCHEMBL8406572 | 0.94 | ALDH1A1 (0.33) | ALDH1A1GAATSHR | |
| SCHEMBL5270639 | 0.88 | ALDH1A1 (0.39) | ALDH1A1GAATSHR | |
| SCHEMBL18486622 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL18486666 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL18486498 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL18486516 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL13678756 | 0.84 | ALDH1A1 (0.33) | ALDH1A1GAATSHR | |
| SCHEMBL4967863 | 0.78 | PIK3CD (0.30) | ALDH1A1 | |
| SCHEMBL6230430 | 0.76 | LPAR3 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515112-B2 | For use in diagnosis and therapy | AMERSHAM PLC (GB) | 2003-02-04 | — | — | US | disclosed |
| US-6329513-B1 | FOR DIAGNOSIS AND THERAPY | NYCOMED AMERSHAM PLC (GB) | 2001-12-11 | — | — | US | disclosed |
| US-6001979-A | AMINO-, IMINO, HYDRAZINO AND AZO SALTS OF TECHNETIUM COMPLEXED WITH NEUTRAL LIGANDS | NYCOMED AMERSHAM PLC (GB) | 1999-12-14 | — | — | US | disclosed |