Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138535 | 0.91 | HTR6 (0.62) | HTR6 | |
| SCHEMBL3399354 | 0.86 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL12428377 | 0.85 | HTR6 (1.00) | HTR6HTR2B | |
| SCHEMBL7134694 | 0.84 | HTR6 (0.78) | HTR6HTR2B | |
| SCHEMBL7136536 | 0.84 | HTR6 (0.78) | HTR6HTR2B | |
| SCHEMBL7138420 | 0.84 | HTR6 (0.78) | HTR6HTR2B | |
| SCHEMBL7137101 | 0.84 | HTR6 (0.75) | HTR6 | |
| SCHEMBL13016762 | 0.83 | HTR6 (0.77) | HTR6HTR2B | |
| SCHEMBL12428299 | 0.82 | HTR6 (0.75) | HTR6HTR2B | |
| SCHEMBL12427021 | 0.82 | HTR6 (0.75) | HTR6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941994-B1 | Pyrazolopyrimidines and pyrazolotriazines with 5-HT6 receptor affinity | HOFFMANN LA ROCHE (CH) | 2003-05-14 | — | — | EP | disclosed |
| US-6194410-B1 | ANTISEROTONINE AGENTS; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | HOFFMAN-LA ROCHE INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0941994-A1 | Pyrazolopyrimidines and pyrazolotriazines with 5-HT6 receptor affinity | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-15 | — | — | EP | disclosed |