Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747667 | 0.85 | KDM4E (0.40) | ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6747666 | 0.85 | KDM4E (0.40) | ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6752012 | 0.84 | HDAC6 (0.37) | ALDH1A1KMT2AKDM4EPELI1MEN1 | |
| SCHEMBL6752015 | 0.84 | HDAC6 (0.37) | ALDH1A1KMT2AKDM4EPELI1MEN1 | |
| SCHEMBL6747150 | 0.82 | HDAC6 (0.35) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL6747151 | 0.82 | HDAC6 (0.35) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8319484 | 0.80 | HDAC6 (0.42) | APPL3MBTL1POLBMAPT | |
| SCHEMBL8319481 | 0.80 | HDAC6 (0.42) | APPL3MBTL1POLBMAPT | |
| SCHEMBL6749215 | 0.79 | HDAC6 (0.34) | ALDH1A1 | |
| SCHEMBL6749216 | 0.79 | HDAC6 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |