Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319481 | 1.00 | HDAC6 (0.42) | HDAC6RARARARBRARGCA2 | |
| SCHEMBL6747555 | 0.89 | HDAC6 (0.44) | HDAC6ICAM1POLBMAPT | |
| SCHEMBL6747171 | 0.88 | PABPC1 (0.41) | HDAC6CA2CA9PTPN1POLB | |
| SCHEMBL6747666 | 0.88 | KDM4E (0.40) | HDAC6CA2CA5ACA9 | |
| SCHEMBL6747174 | 0.86 | HDAC6 (0.34) | HDAC6L3MBTL1MAPT | |
| SCHEMBL6749127 | 0.86 | MAPT (0.39) | HDAC6MKNK2MAPT | |
| SCHEMBL6749131 | 0.86 | MAPT (0.39) | HDAC6MKNK2MAPT | |
| SCHEMBL6752012 | 0.84 | HDAC6 (0.37) | HDAC6L3MBTL1MAPT | |
| SCHEMBL6752015 | 0.84 | HDAC6 (0.37) | HDAC6L3MBTL1MAPT | |
| SCHEMBL8315505 | 0.84 | HDAC6 (0.45) | HDAC6POLBL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |