Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 4/20 | 0.61 |
| ▸ | IKBKB | O14920 | 4/20 | 0.61 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.61 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.61 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512152 | 0.87 | BCAT2 (0.59) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL28115051 | 0.86 | IKBKB (0.54) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL164881 | 0.84 | BCAT2 (0.71) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL3433069 | 0.84 | BCAT2 (0.71) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| Hydrochloric Acid SCHEMBL4597839 | 0.82 | BCAT2 (0.69) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| Hydrochloric Acid SCHEMBL29710331 | 0.82 | BCAT2 (0.69) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| Hydrochloric Acid SCHEMBL9027847 | 0.82 | BCAT2 (0.69) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL3791160 | 0.82 | BCAT2 (0.53) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL2782245 | 0.81 | CDC7 (0.50) | CHUKIKBKBIKBKEPKMYT1BCAT2 | |
| SCHEMBL6448102 | 0.81 | BCAT2 (0.67) | CHUKIKBKBIKBKEPKMYT1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309590-A1 | AZAINDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-05-14 | — | — | EP | claimed |
| WO-2001098299-A1 | AZAINDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-27 | — | — | WO | claimed |