Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27971095 | 0.98 | AKR1C3 (0.59) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| Toluene SCHEMBL28189299 | 0.90 | AKR1C3 (0.56) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL16792377 | 0.90 | AKR1C3 (0.51) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL1941132 | 0.89 | AKR1C3 (0.58) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL11000519 | 0.89 | AKR1C3 (0.54) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| Ethyl Acetate SCHEMBL5560814 | 0.85 | KMT2A (0.51) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL28598896 | 0.85 | TSHR (0.44) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL29118338 | 0.84 | AKR1C3 (0.71) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL30517803 | 0.84 | AKR1C3 (0.66) | AKR1C3KMONR4A2KMT2AMRGPRX4 | |
| SCHEMBL5235780 | 0.84 | AKR1C3 (0.66) | AKR1C3KMONR4A2KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2041 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909060-A | Preparation process of N- (2-acetamido) -2-aminoethanesulfonic acid | 苏州亚科科技股份有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-108727521-A | A kind of preparation method of polymerization inhibitor | 雷春生 | 2018-11-02 | — | — | CN | claimed |
| CN-105061463-B | A kind of nine yuan of fused-ring derivatives and its synthetic method and application | 华南理工大学 | 2018-09-14 | — | — | CN | claimed |
| CN-107903283-A | By trimethyl（Vinyl）The method that silane synthesizes 2 phenyl, 2 trimethyl silicon substrate chloroacetic chloride | 武汉药明康德新药开发有限公司 | 2018-04-13 | — | — | CN | claimed |
| CN-105949412-B | A kind of preparation method and application of the block polymer containing TEMPO | 河北科技大学 | 2018-04-10 | — | — | CN | claimed |
| CN-107721189-A | High-k zirconia nanocrystals body/polyimide composite film and preparation method thereof | 嘉兴学院 | 2018-02-23 | — | — | CN | claimed |
| CN-107629313-A | A kind of car deceleration device rubber parts | 无为县大江橡塑制品有限公司 | 2018-01-26 | — | — | CN | claimed |
| CN-107531672-A | CHEMICAL PROCESS FOR PREPARING PYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | 诺华股份有限公司 | 2018-01-02 | — | — | CN | claimed |
| CN-107428688-A | Efficient Synthesis of Carbazole Derivatives | 汉阳大学校ERICA产学协力团 | 2017-12-01 | — | — | CN | claimed |
| CN-105646300-B | A kind of preparation method of the 2 pungent naphthoquinones of sulfoxide 1,4 | 黑龙江八农垦大学 | 2017-11-10 | — | — | CN | claimed |
| WO-2002095098-A1 | MODIFICATION OF CARBON NANOTUBES BY OXIDATION WITH PEROXYGEN COMPOUNDS | HYPERION CATALYSIS INTERNATIONAL, INC. (US) | 2002-11-28 | — | — | WO | claimed |
| EP-1095037-B1 | PROCESS OF SYNTHESIS OF 5-METHOXY- 2- (4-METHOXY- 3,5-DIMETHYL- 2-PYRIDYL)METHYL]SULFINYL-1H-BENZIMIDAZOLE | LEK TOVARNA FARMACEVTSKIH (SI) | 2002-04-17 | — | — | EP | claimed |
| CN-1040980-C | Second messenger cell signaling inhibitors | CELL THERAPEUTICS INC (US) | 1998-12-02 | — | — | CN | claimed |
| US-5571907-A | EPOXIDATION OF ALLYL SACCHARIDES | HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) | 1996-11-05 | — | — | US | claimed |
| EP-0395357-B1 | Polyamines useful as antagonists of excitatory amino acid neurotransmitters and/or as blockers of calcium channels | PFIZER (US) | 1995-12-20 | — | — | EP | claimed |
| EP-0533752-A1 | IMPROVED METHOD FOR SYNTHESIS | Astra Aktiebolag (SE) | 1993-03-31 | — | — | EP | claimed |
| WO-1991018895-A1 | IMPROVED METHOD FOR SYNTHESIS | AKTIEBOLAGET ASTRA (SE) | 1991-12-12 | — | — | WO | claimed |
| EP-0240164-A2 | Preparation of azetidinones | SCHERING CORPORATION (US) | 1987-10-07 | — | — | EP | claimed |
| US-4119625-A | Process for the manufacture of steroid carboxylic acids and the esters thereof | CIBA-GEIGY CORPORATION (US) | 1978-10-10 | — | — | US | claimed |
| US-3950404-A | Method for preparation of sulfinic acids | GESELLSCHAFT FUR KERNFORSCHUNG MBH (DT) | 1976-04-13 | — | — | US | claimed |