Toluene

Toluene

SCHEMBL28189299

Cc1ccccc1.O=C(O)c1cccc(OOCl)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.56
NR4A2 P43354 5/20 0.49
KMT2A Q03164 1/20 0.49
KMO O15229 2/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MRGPRX4 Q96LA9 1/20 0.44
NR1H4 Q96RI1 2/20 0.44
POLB P06746 1/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71432 0.90 AKR1C3 (0.61) AKR1C3NR4A2KMT2AKMONPC1
Water SCHEMBL27971095 0.89 AKR1C3 (0.59) AKR1C3NR4A2KMT2AKMONPC1
SCHEMBL11000519 0.83 AKR1C3 (0.54) AKR1C3NR4A2KMT2AKMONPC1
Ethyl Acetate SCHEMBL5560814 0.82 KMT2A (0.51) AKR1C3NR4A2KMT2AKMONPC1
SCHEMBL16792377 0.81 AKR1C3 (0.51) AKR1C3NR4A2KMT2AKMONPC1
SCHEMBL1941132 0.80 AKR1C3 (0.58) AKR1C3NR4A2KMT2AKMONPC1
SCHEMBL29118338 0.79 AKR1C3 (0.71) AKR1C3NR4A2KMT2AKMONPC1
Isophthalic Acid SCHEMBL28470879 0.79 KMO (0.57) AKR1C3KMT2AKMOPOLB
SCHEMBL2857675 0.77 AKR1C3 (0.73) AKR1C3KMT2AKMONPC1RAB9A
SCHEMBL13369193 0.76 AKR1C3 (0.61) AKR1C3NR4A2KMT2AKMONPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428688-A Efficient Synthesis of Carbazole Derivatives 汉阳大学校ERICA产学协力团 2017-12-01 CN disclosed