Thioglycolic Acid

Thioglycolic Acid

SCHEMBL7143486

CCCC.NC(N)=S.O=C(O)CS

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
AKR1B1 P15121 1/20 0.35
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
GPR84 Q9NQS5 7/20 0.33
PPARG P37231 7/20 0.33
PPARD Q03181 7/20 0.33
PPARA Q07869 7/20 0.33
HDAC11 Q96DB2 5/20 0.33
TSHR P16473 5/20 0.33
PTPN1 P18031 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL3284619 0.86
Thioglycolic Acid SCHEMBL476547 0.86 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL28280313 0.78 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL23045257 0.77
Propionic Acid SCHEMBL28954363 0.77
Thioglycolic Acid SCHEMBL11819584 0.77
Thioglycolic Acid SCHEMBL7143489 0.77 ALDH1A1 (0.41) FFAR3KMT2ACYP1A2MAPTTSHR
Thioglycolic Acid SCHEMBL11854674 0.76
Thioglycolic Acid SCHEMBL10607018 0.76
Thioglycolic Acid SCHEMBL16795985 0.76 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6521028-B1 Quaternary ammonium salts, particularly pyridinium and quinolinium salts. By preparing these salts in a solvent selected from the group consisting of propylene glycols, propylene glycol ethers and mixtures thereof, the production HYDROCHEM INDUSTRIAL SERVICES, INC. 2003-02-18 US claimed