Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141036 | 0.90 | PTGS2 (0.49) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7146351 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7147709 | 0.88 | P2RY6 (0.54) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7150702 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7144943 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7150707 | 0.86 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL18060585 | 0.85 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7148451 | 0.80 | P2RY6 (0.54) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7150705 | 0.80 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL29528023 | 0.79 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |