Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28893744 | 0.82 | IDO1 (0.44) | IDO1ALDH1A1TSHRTDP1RXRA | |
| SCHEMBL8209322 | 0.78 | PTGDR2 (0.38) | — | |
| SCHEMBL28896167 | 0.77 | ALDH1A1 (0.39) | IDO1ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL12894334 | 0.77 | IDO1 (0.40) | IDO1ALDH1A1TSHRTDP1RXRA | |
| SCHEMBL3685038 | 0.74 | IDO1 (0.44) | IDO1ALDH1A1TSHRTDP1RXRA | |
| SCHEMBL14261314 | 0.74 | TSHR (0.56) | IDO1ALDH1A1TSHRTDP1RXRA | |
| SCHEMBL22468793 | 0.73 | CYP1A2 (0.43) | TSHRTDP1 | |
| SCHEMBL22468792 | 0.73 | CYP1A2 (0.43) | TSHRTDP1 | |
| SCHEMBL8274416 | 0.72 | IDO1 (0.37) | IDO1ALDH1A1TSHRTDP1RXRA | |
| SCHEMBL14261313 | 0.72 | MAPT (0.39) | IDO1ALDH1A1TSHRTDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |