Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13317673 | 0.74 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL13298446 | 0.69 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL11741928 | 0.69 | — | — | |
| SCHEMBL2548227 | 0.69 | — | — | |
| SCHEMBL16842417 | 0.69 | — | — | |
| SCHEMBL27694874 | 0.67 | CYP19A1 (0.51) | CYP19A1HTT | |
| SCHEMBL1039872 | 0.67 | CYP19A1 (0.45) | CYP19A1HTT | |
| SCHEMBL13243996 | 0.67 | CYP19A1 (0.45) | CYP19A1HTT | |
| SCHEMBL19773983 | 0.67 | CYP19A1 (0.45) | CYP19A1HTT | |
| SCHEMBL12600213 | 0.67 | CYP19A1 (0.45) | CYP19A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998455-B1 | DIHOMO-SECO-CHOLESTANES WITH TWO UNSATURATED BONDS IN THE SIDE CHAIN | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-6153605-A | Arylsecocholadiene derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0998455-A1 | DIHOMO-SECO-CHOLESTANES WITH TWO UNSATURATED BONES IN THE SIDE CHAIN | F.HOFFMANN-LA ROCHE AG (CH) | 2000-05-10 | — | — | EP | disclosed |
| EP-0771789-B1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | EP | disclosed |
| EP-0977734-A2 | ARYLSECOCHOLADIENE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-02-09 | — | — | EP | disclosed |
| US-5994569-A | USEFUL IN THE TREATMENT OR PREVENTION OF VITAMIN D DEPENDENT DISORDERS AND OF IL-12-DEPENDENT AUTOIMMUNE DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5905074-A | SKIN DISORDERS, ANTITUMOR AGENTS, VITAMIN D DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1999-05-18 | — | — | US | disclosed |
| WO-1999003828-A1 | DIHOMO-SECO-CHOLESTANES WITH TWO UNSATURATED BONES IN THE SIDE CHAIN | F.HOFFMANN-LA ROCHE AG (CH) | 1999-01-28 | — | — | WO | disclosed |
| WO-1998047866-A2 | ARYLSECOCHOLADIENE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-29 | — | — | WO | disclosed |
| EP-0771789-A1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |