Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | VDR | P11473 | 3/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039872 | 1.00 | CYP19A1 (0.45) | CYP19A1VDRHTT | |
| SCHEMBL13243996 | 1.00 | CYP19A1 (0.45) | CYP19A1VDRHTT | |
| SCHEMBL19773983 | 1.00 | CYP19A1 (0.45) | CYP19A1VDRHTT | |
| SCHEMBL14473784 | 0.86 | CYP19A1 (0.41) | CYP19A1VDR | |
| SCHEMBL8993014 | 0.82 | CYP19A1 (0.37) | CYP19A1VDR | |
| SCHEMBL8993016 | 0.82 | CYP19A1 (0.37) | CYP19A1VDR | |
| SCHEMBL8992727 | 0.80 | CYP19A1 (0.39) | CYP19A1VDR | |
| SCHEMBL8992724 | 0.80 | CYP19A1 (0.39) | CYP19A1VDR | |
| SCHEMBL8992723 | 0.79 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL8992719 | 0.79 | CYP19A1 (0.34) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943601-B2 | 2-methylene-20-methyl-19,24,25,26,27-pentanor-vitamin D analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-05-17 | — | — | US | disclosed |
| US-7763598-B2 | 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-07-27 | — | — | US | disclosed |
| US-20090170822-A1 | 2-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-07-02 | — | — | US | disclosed |
| US-20070238703-A1 | 1alpha-Hydroxy-2-(3'-Hydroxypropylidene)-19-Nor-Vitamin D Compounds with a 1,1-Dimethylpropyl Side Chain | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238703-A1 | 1alpha-Hydroxy-2-(3'-Hydroxypropylidene)-19-Nor-Vitamin D Compounds with a 1,1-Dimethylpropyl Side Chain | CYP24A1, CYP27B1, VDR | CYP19A1 1133/4885VDR 3/4885HTT 4194/4885 |
| US-20090170822-A1 | 2-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs | VDR, CYP24A1, CYP2R1 | CYP19A1 1467/4885VDR 1/4885HTT 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.