Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PPM1D | O15297 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144078 | 1.00 | CDC25A (0.35) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL13343109 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL8211097 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL8209310 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL14107826 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL10440704 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL8209307 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL8674922 | 0.94 | CDC25A (0.40) | CDC25ACDC25BPPM1DCYP17A1 | |
| SCHEMBL7145023 | 0.85 | CDC25A (0.40) | CDC25ACDC25BPPM1D | |
| SCHEMBL8207424 | 0.85 | PPM1D (0.34) | CDC25ACDC25BPPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998455-B1 | DIHOMO-SECO-CHOLESTANES WITH TWO UNSATURATED BONDS IN THE SIDE CHAIN | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-6153605-A | Arylsecocholadiene derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |
| US-5994569-A | USEFUL IN THE TREATMENT OR PREVENTION OF VITAMIN D DEPENDENT DISORDERS AND OF IL-12-DEPENDENT AUTOIMMUNE DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1999-11-30 | — | — | US | disclosed |