Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | PPM1D | O15297 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440704 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL8209310 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL13343109 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL8674922 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL14107826 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL8211097 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1PPM1DGPBAR1 | |
| SCHEMBL7144084 | 0.94 | CDC25A (0.35) | CDC25ACDC25BCYP17A1PPM1D | |
| SCHEMBL7144078 | 0.94 | CDC25A (0.35) | CDC25ACDC25BCYP17A1PPM1D | |
| SCHEMBL7764768 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL7765817 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915242-B2 | eczema, hypercalcemia, hyperparathyroidism, sarcoidosis, or vitamin D intoxication | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-03-29 | — | — | US | disclosed |
| US-6153605-A | Arylsecocholadiene derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |