Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139605 | 1.00 | KDM4E (0.60) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL6239035 | 1.00 | KDM4E (0.60) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL13394476 | 0.86 | KDM4E (0.56) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL13322831 | 0.86 | KDM4E (0.56) | KDM4EHPGDALDH1A1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL22828959 | 0.84 | HPGD (0.56) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL11285599 | 0.84 | KDM4E (0.45) | KDM4EHPGDALDH1A1CD274NR4A2 | |
| SCHEMBL7141884 | 0.83 | KDM4E (0.47) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL6245180 | 0.83 | POLB (0.58) | KDM4EKMT2ANR4A2MEN1 | |
| SCHEMBL29242881 | 0.83 | POLB (0.58) | KDM4EKMT2ANR4A2MEN1 | |
| SCHEMBL6243532 | 0.83 | POLB (0.58) | KDM4EKMT2ANR4A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |