Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144643 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7139605 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL6239035 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL2398120 | 0.80 | KMT2A (0.66) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL2398115 | 0.80 | KMT2A (0.66) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL21345586 | 0.79 | TAAR1 (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10348018 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL18997892 | 0.77 | KMT2A (0.57) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5285749 | 0.74 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5966846 | 0.74 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |
| EP-1098871-A1 | $g(a)-AMINO ACID PHENYL ESTER DERIVATIVES | Akzo Nobel N.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005196-A1 | α-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL N.V. (NL) | 2000-02-03 | — | — | WO | disclosed |