Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7148146 | 0.99 | F2 (0.46) | F2F11PTGER4PLGPRSS1 | |
| SCHEMBL7247787 | 0.87 | F2 (0.35) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7139402 | 0.86 | PTGER4 (0.36) | F2PTGER4 | |
| Hydrochloric Acid SCHEMBL7158175 | 0.86 | F2 (0.36) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7104093 | 0.85 | NPSR1 (0.34) | F2PTGER4PRSS1 | |
| Hydrochloric Acid SCHEMBL7144181 | 0.84 | NPSR1 (0.34) | F2PTGER4 | |
| SCHEMBL7361838 | 0.84 | PTGER4 (0.35) | F2PTGER4 | |
| Hydrochloric Acid SCHEMBL7142554 | 0.84 | PTGER4 (0.35) | F2PTGER4 | |
| SCHEMBL7100961 | 0.83 | XIAP (0.35) | F2PTGER4 | |
| SCHEMBL7101675 | 0.83 | PTGER4 (0.35) | F2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |