Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 9/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | MC1R | Q01726 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7144181 | 0.99 | NPSR1 (0.34) | NPSR1PTGER4F2MC3RMC1R | |
| SCHEMBL7465555 | 0.88 | MC3R (0.31) | NPSR1MC3RMC1RCYP3A4 | |
| Hydrochloric Acid SCHEMBL7156752 | 0.87 | MC3R (0.31) | NPSR1MC3RMC1R | |
| SCHEMBL7139402 | 0.86 | PTGER4 (0.36) | PTGER4F2MC3RMC1RMEN1 | |
| SCHEMBL7144656 | 0.85 | F2 (0.45) | PTGER4F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7148146 | 0.84 | F2 (0.46) | PTGER4F2PRSS1 | |
| SCHEMBL7361838 | 0.84 | PTGER4 (0.35) | PTGER4F2MC3RMC1RCYP3A4 | |
| Hydrochloric Acid SCHEMBL7142554 | 0.84 | PTGER4 (0.35) | PTGER4F2MC3RMC1RCYP3A4 | |
| SCHEMBL7101287 | 0.83 | MC3R (0.35) | PTGER4F2MC3RMC1RPRSS1 | |
| SCHEMBL7104014 | 0.83 | OPRM1 (0.37) | PTGER4F2CYP3A4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |