Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146656 | 0.94 | LSS (0.60) | LSS | |
| SCHEMBL7149010 | 0.88 | LSS (0.59) | LSS | |
| SCHEMBL7150712 | 0.87 | LSS (0.48) | LSS | |
| SCHEMBL7142573 | 0.87 | LSS (0.57) | LSS | |
| SCHEMBL7145197 | 0.86 | LSS (0.57) | LSS | |
| SCHEMBL7152838 | 0.83 | LSS (0.55) | LSS | |
| SCHEMBL5038612 | 0.82 | LSS (0.70) | LSS | |
| SCHEMBL7152044 | 0.82 | LSS (0.59) | LSS | |
| SCHEMBL7145283 | 0.81 | LSS (0.54) | LSS | |
| SCHEMBL8478774 | 0.81 | LSS (0.69) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334094-A1 | CHOLESTEROL LOWERING BENZO[B]THIOPHENES AND BENZO[D]ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036584-A1 | CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-10 | — | — | WO | disclosed |