Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 15/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145649 | 0.99 | EBP (0.49) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7139953 | 0.92 | EBP (0.54) | EBPSIGMAR1HRH3ESR1ESR2 | |
| SCHEMBL7144833 | 0.87 | ESR1 (0.54) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7138152 | 0.86 | HRH3 (0.48) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7136715 | 0.86 | ESR1 (0.55) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7144464 | 0.86 | CHRM3 (0.39) | EBPSIGMAR1KCNH2ESR1 | |
| SCHEMBL7146901 | 0.85 | EBP (0.49) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7145591 | 0.84 | HRH3 (0.46) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7143811 | 0.83 | HRH3 (0.46) | EBPSIGMAR1HRH3KCNH2ESR1 | |
| SCHEMBL7144261 | 0.83 | HRH3 (0.46) | EBPSIGMAR1HRH3KCNH2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832880-B1 | Dihydrobenzofluorene compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0832880-A1 | Dihydrobenzofluorene compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |