Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 17/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141028 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6092709 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL6092721 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7150416 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7150453 | 0.80 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL7140520 | 0.79 | PTGS2 (0.52) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL7143504 | 0.79 | P2RY6 (0.42) | PTGS2PTGS1 | |
| SCHEMBL7144648 | 0.79 | P2RY6 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7143301 | 0.79 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL5644742 | 0.78 | PTGS2 (0.46) | CA12CA9PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |