Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566554 | 0.87 | GAA (0.48) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| Methylene Chloride SCHEMBL29003610 | 0.80 | GAA (0.39) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL28533846 | 0.79 | GAA (0.41) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL12545892 | 0.77 | PIK3CD (0.48) | GAAL3MBTL1POLBSMN1; SMN2P2RX7 | |
| SCHEMBL7148826 | 0.76 | GAA (0.46) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL10967106 | 0.76 | GAA (0.42) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL12208453 | 0.76 | GAA (0.42) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL7139392 | 0.76 | GAA (0.42) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL12709502 | 0.76 | GAA (0.42) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 | |
| SCHEMBL22017935 | 0.76 | GAA (0.39) | GAAL3MBTL1POLBSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100800-B1 | NOVEL C-2 S/O- AND S/N FORMALDEHYDE ACETAL DERIVATIVES OF CARBAPENEM-3-CARBOXYLIC ACIDS AND THEIR USE AS ANTIBIOTICS AND BETA-LACTAMASE INHIBITORS | PFAENDLER HANS RUDOLF PROF (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6482818-B2 | ANTIBIOTIC | PFAENDLER HANS RUDOLF (DE) | 2002-11-19 | — | — | US | disclosed |
| US-20010031749-A1 | Novel C-2 S/O-and S/N formaldehyde Acetal Derivatives of Carbapenem-3-carboxylic acids and their use as antibiotics and beta-lactamase inhibitors | PFAENDLER HANS RUDOLF (DE) | 2001-10-18 | — | — | US | disclosed |
| EP-1100800-A1 | NOVEL C-2 S/O- AND S/N FORMALDEHYDE ACETAL DERIVATIVES OF CARBAPENEM-3-CARBOXYLIC ACIDS AND THEIR USE AS ANTIBIOTICS AND BETA-LACTAMASE INHIBITORS | Pfaendler, Hans Rudolf, Prof. (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006574-A1 | NOVEL C-2 S/O- AND S/N FORMALDEHYDE ACETAL DERIVATIVES OF CARBAPENEM-3-CARBOXYLIC ACIDS AND THEIR USE AS ANTIBIOTICS AND β-LACTAMASE INHIBITORS | PFAENDLER HANS RUDOLF (DE) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976752-A1 | C-2 S/O- and S/N-Formaldehyde acetal derivatives of carbapenem antibiotics | Pfaendler, Hans Rudolf, Prof. (DE) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031749-A1 | Novel C-2 S/O-and S/N formaldehyde Acetal Derivatives of Carbapenem-3-carboxylic acids and their use as antibiotics and beta-lactamase inhibitors | H1-2, SULT1E1, H1-0 | GAA 456/4885L3MBTL1 1727/4885POLB 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.