Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146568 | 0.89 | IKBKB (0.38) | TLR8IKBKBTUBB4ATUBBTUBA3C | |
| SCHEMBL7043840 | 0.89 | PARP1 (0.43) | IKBKBCDC7HPGDRIPK2SLC9A1 | |
| SCHEMBL7041861 | 0.89 | IKBKB (0.46) | TLR8IKBKBCDC7HPGD | |
| SCHEMBL6876511 | 0.88 | FYN (0.37) | TLR8IKBKBCDC7TUBB4ATUBB | |
| SCHEMBL7144535 | 0.88 | NTRK1 (0.40) | TLR8IKBKBCDC7TUBB4ATUBB | |
| SCHEMBL7146854 | 0.87 | PDE4D (0.43) | IKBKBFYN | |
| SCHEMBL7150015 | 0.85 | KDM4E (0.49) | SLC9A1FYNPARP1 | |
| SCHEMBL7144539 | 0.85 | FYN (0.46) | DHODHFYNPARP1 | |
| SCHEMBL7041042 | 0.85 | HPGD (0.39) | POLBTSHRHPGDHSD17B10FYN | |
| SCHEMBL7043074 | 0.83 | NTRK1 (0.45) | IKBKBCDC7HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514989-B1 | Has a good affinity to the adenosine receptor and can therefore be used for the treatment or protection of diseases mediated by this receptor | HOFFMANN-LA ROCHE INC. | 2003-02-04 | — | — | US | disclosed |