Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365552 | 0.80 | MAPT (0.62) | MAPTKMT2ALMNAMEN1TSHR | |
| SCHEMBL7147079 | 0.78 | KMT2A (0.43) | MAPTNPSR1KMT2ALMNAMEN1 | |
| SCHEMBL12956195 | 0.73 | HCRTR2 (0.68) | MAPTNPSR1KMT2ALMNAMEN1 | |
| Formic Acid SCHEMBL27654382 | 0.72 | HCRTR2 (0.48) | MAPTNPSR1KMT2ALMNAMEN1 | |
| SCHEMBL3368625 | 0.70 | TSHR (0.58) | MAPTKMT2ALMNAMEN1TSHR | |
| SCHEMBL3365718 | 0.70 | KMT2A (0.66) | MAPTKMT2ALMNAMEN1HCRTR2 | |
| SCHEMBL1039637 | 0.69 | HCRTR2 (1.00) | MAPTLMNATSHRL3MBTL1HCRTR2 | |
| SCHEMBL16557548 | 0.68 | MAPT (0.84) | MAPTNPSR1KMT2ALMNAMEN1 | |
| SCHEMBL1040690 | 0.68 | HCRTR2 (0.72) | MAPTLMNATSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL1040053 | 0.68 | HCRTR2 (0.82) | MAPTLMNATSHRL3MBTL1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002032864-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-25 | — | — | WO | disclosed |