Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369941 | 0.81 | OXTR (0.54) | KMT2AMAPTOXTRTSHRLMNA | |
| SCHEMBL3366190 | 0.81 | OXTR (0.54) | KMT2AMAPTOXTRTSHRLMNA | |
| SCHEMBL7145996 | 0.78 | MAPT (0.55) | KMT2AMAPTMEN1HTTNPSR1 | |
| SCHEMBL3366811 | 0.67 | KMT2A (0.47) | KMT2AMAPTOXTRLMNAHCRTR2 | |
| SCHEMBL3369962 | 0.67 | OXTR (0.55) | KMT2AMAPTOXTRLMNAALDH1A1 | |
| SCHEMBL5644407 | 0.66 | OXTR (0.57) | KMT2AMAPTOXTRTSHRLMNA | |
| SCHEMBL5675703 | 0.65 | ALDH1A1 (0.51) | KMT2AMAPTMEN1HTTNPSR1 | |
| SCHEMBL13588819 | 0.63 | ALDH1A1 (0.44) | KMT2AMAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL419398 | 0.63 | HSD17B10 (0.54) | MAPTNPSR1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL29469832 | 0.63 | CA1 (0.60) | MAPTNPSR1L3MBTL1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002032864-A1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-25 | — | — | WO | disclosed |