Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94409 | 0.91 | — | — | |
| SCHEMBL28069377 | 0.88 | NOS3 (0.32) | — | |
| SCHEMBL30355316 | 0.88 | NOS3 (0.32) | — | |
| SCHEMBL29585390 | 0.85 | — | — | |
| SCHEMBL94169 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL28660339 | 0.83 | HRH4 (0.35) | NPC1 | |
| Water SCHEMBL8928299 | 0.83 | HRH4 (0.35) | NPC1 | |
| Hydrochloric Acid SCHEMBL30378836 | 0.83 | HRH4 (0.35) | NPC1 | |
| SCHEMBL95816 | 0.83 | — | — | |
| SCHEMBL27597372 | 0.81 | HSP90AA1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6648924-B2 | Quaternary indole or pyridine substituted hydrazone derivatives; vivid colors ranging from yellow to orange | KAO CORPORATION (JP) | 2003-11-18 | — | — | US | disclosed |
| EP-0586523-A4 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | UNIV YALE (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0586523-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |