SCHEMBL7146522

SCHEMBL7146522

CO[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
CA9 Q16790 6/20 0.39
CA12 O43570 5/20 0.39
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
TSHR P16473 2/20 0.35
POLB P06746 2/20 0.34
CYP2D6 P10635 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
OGA O60502 1/20 0.33
THRB P10828 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NR3C1 P04150 1/20 0.33
FYN P06241 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADRA2B P18089 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7153104 1.00 ALDH1A1 (0.42) ALDH1A1CA9CA12CA1CA2
SCHEMBL20581903 1.00 ALDH1A1 (0.42) ALDH1A1CA9CA12CA1CA2
SCHEMBL16869447 1.00 ALDH1A1 (0.42) ALDH1A1CA9CA12CA1CA2
SCHEMBL21819708 1.00 ALDH1A1 (0.42) ALDH1A1CA9CA12CA1CA2
SCHEMBL16869483 0.90 CA9 (0.35) ALDH1A1CA9CA12CA1CA2
SCHEMBL21510391 0.87 TSHR (0.44) ALDH1A1CA9CA12CA1CA2
SCHEMBL7151917 0.87 TSHR (0.44) ALDH1A1CA9CA12CA1CA2
SCHEMBL7154470 0.87 TSHR (0.44) ALDH1A1CA9CA12CA1CA2
SCHEMBL8358880 0.87 TSHR (0.44) ALDH1A1CA9CA12CA1CA2
SCHEMBL7152812 0.87 TSHR (0.44) ALDH1A1CA9CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014203198-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND RENAL COMPLICATIONS KANDULA MAHESH (IN) 2014-12-24 WO disclosed
US-6562514-B1 Stabilized vanadium electrolyte solutions for all-vanadium redox cells and batteries PINNACLE VRB LIMITED (AU) 2003-05-13 US disclosed
US-6468688-B2 CHARGING, DISCHARGING EFFICIENCY; VANADIUM ELECTROLYTE PINNACLE VRB LIMITED (AU) 2002-10-22 US disclosed
US-20010028977-A1 Charging, discharging efficiency; vanadium electrolyte JD HOLDING INC. (KY) 2001-10-11 US disclosed
US-6143443-A ALL-VANADIUM REDOX BATTERY, COMPRISING THE STABILIZED ELECTROLYTE PINNACLE ARB LIMITED (AU) 2000-11-07 US disclosed