SCHEMBL7147137

SCHEMBL7147137

CC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1.CC1=NN(c2c(F)c(F)c(F)c(F)c2F)C(=O)C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.50
KMT2A Q03164 9/20 0.50
ALDH1A1 P00352 7/20 0.50
MEN1 O00255 7/20 0.50
KDM4E B2RXH2 6/20 0.50
TDP1 Q9NUW8 6/20 0.50
GAA P10253 4/20 0.50
HTT P42858 3/20 0.50
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 4/20 0.44
POLB P06746 3/20 0.44
CASP6 P55212 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
CYP1A2 P05177 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
CHRM1 P11229 1/20 0.42
TSHR P16473 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1110494 0.91 MAPT (0.58) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL1110348 0.84 MAPT (0.50) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL3190354 0.78 MAPT (0.53) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL4339175 0.78 MAPT (0.47) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17261660 0.75 MAPT (0.62) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL5462610 0.75 MAPT (0.72) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL4331102 0.72 KMT2A (0.68) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL4013719 0.72 KMT2A (0.42) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL8417603 0.72 MAPT (0.54) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL8168676 0.72 KMT2A (0.49) MAPTKMT2AALDH1A1MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030073017-A1 For printing images BANK OF AMERICA, N.A., AS AGENT 2003-04-17 US disclosed