SCHEMBL4013719

SCHEMBL4013719

NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.42
MAPT P10636 7/20 0.42
MEN1 O00255 6/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
GAA P10253 2/20 0.42
PTGS1 P23219 1/20 0.41
HTT P42858 2/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 2/20 0.39
THRB P10828 1/20 0.39
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CD274 Q9NZQ7 4/20 0.35
PDCD1 Q15116 3/20 0.35
KDR P35968 3/20 0.35
SRC P12931 2/20 0.35
CASP6 P55212 2/20 0.32
CTDSP1 Q9GZU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9525446 0.83 TDP1 (0.43) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL10889560 0.82 MAPT (0.51) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL8169439 0.81 L3MBTL1 (0.41) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL1110494 0.79 MAPT (0.58) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL11182553 0.79 PDCD1 (0.56) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL22909489 0.78 CD274 (0.57) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL14608039 0.76 MAPT (0.39) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL8417603 0.76 MAPT (0.54) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL6757551 0.76 MAPT (0.48) KMT2AMAPTMEN1L3MBTL1GAA
SCHEMBL8168676 0.76 KMT2A (0.49) KMT2AMAPTMEN1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1332357-B1 LIGAND BASED SOLUTION ASSAY FOR LOW CONCENTRATION ANALYTES SAUNDERS ALEX M (US) 2006-05-24 EP claimed
US-6936429-B2 Ligand based solution assay for low concentration analytes CHRONOMED, INC. (US) 2005-08-30 US claimed
EP-1332357-A4 LIGAND BASED SOLUTION ASSAY FOR LOW CONCENTRATION ANALYTES SAUNDERS ALEX M (US) 2004-07-14 EP claimed
US-20040115751-A1 Ligand based solution assay for low concentration analytes CHRONOMED, INC. 2004-06-17 US claimed
US-6682903-B2 DETECTING PREFERENTIAL PARTICLES IN SOLUTION; GENERATE REACTION MIXTURE, INCUBATE WITH SAMPLE, DETECT GENERATION OF COLORED REACTION PRODUCT, CORRELATE PRESENCE OF PARTICLE WITH COLORED REACTION PRODUCT SAUNDERS ALEX M (US) 2004-01-27 US claimed
EP-1332357-A1 LIGAND BASED SOLUTION ASSAY FOR LOW CONCENTRATION ANALYTES Saunders, Alex M. (US) 2003-08-06 EP claimed
US-20020123085-A1 Ligand based solution assay for low concentration analytes SAUNDERS ALEX M (US) 2002-09-05 US claimed
WO-2002033396-A1 LIGAND BASED SOLUTION ASSAY FOR LOW CONCENTRATION ANALYTES SAUNDERS ALEX M (US) 2002-04-25 WO claimed
US-7544722-B2 aquatic environment; block polymers having a carbon and/or silicone backbone with a pendant biocidal/fouling release group; dimethylsiloxane-vinylmethyl siloxane-Triclosan methacrylate ester block polymer; isoprene-triclosan methacrylate-methacrylic acid with pendant polydimethylsiloxane at the carboxy NDSU RESEARCH FOUNDATION (US) 2009-06-09 US disclosed
US-7396641-B2 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2008-07-08 US disclosed
US-20080076078-A1 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080057449-A1 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
EP-1663531-A4 ANTI-FOULING MATERIALS NDSU RES FOUNDATION (US) 2007-11-28 EP disclosed
US-20070231754-A1 Black and white photothermographic material FUJIFILM CORPORATION 2007-10-04 US disclosed
EP-1049682-A1 OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION Versicor, Inc. (US) 2000-11-08 EP disclosed
WO-1999037630-A1 OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION VERSICOR, INC. (US) 1999-07-29 WO disclosed
WO-1998022822-A9 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS 1998-09-11 WO disclosed
WO-1998022822-A1 PHOTOGRAPHIC COLOR COUPLERS USED AS CYTOCHEMICAL CONTRAST MARKERS APPLIED IMAGING CORPORATION (US) 1998-05-28 WO disclosed
US-4474870-A Silver halide color photographic light-sensitive material FUJI PHOTO FILM COMPANY LIMITED (JP) 1984-10-02 US disclosed
US-4435503-A POLYMER COUPLER AND FORMALDEHYDE SCAVENGER FUJI PHOTO FILM CO., LTD. (JP) 1984-03-06 US disclosed