Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062285 | 0.85 | KCNH2 (0.61) | KCNH2TDP1L3MBTL1HRH1CYP1A2 | |
| SCHEMBL10369402 | 0.81 | KCNH2 (0.47) | KCNH2PDPK1TDP1CYP1A2CYP2D6 | |
| SCHEMBL14733134 | 0.81 | CCR1 (0.50) | KCNH2TDP1L3MBTL1APPPDE10A | |
| SCHEMBL9526361 | 0.80 | KDM4E (0.55) | KCNH2TDP1L3MBTL1HRH1CYP1A2 | |
| SCHEMBL248521 | 0.80 | KCNH2 (0.95) | KCNH2TDP1L3MBTL1CYP19A1GPR84 | |
| SCHEMBL586654 | 0.80 | KCNH2 (0.49) | KCNH2PDPK1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL1819112 | 0.78 | KCNH2 (0.59) | KCNH2PDPK1TDP1L3MBTL1HRH1 | |
| SCHEMBL24973117 | 0.78 | KCNH2 (1.00) | KCNH2CYP19A1GPR84 | |
| SCHEMBL6463178 | 0.78 | KCNH2 (1.00) | KCNH2CYP19A1GPR84 | |
| SCHEMBL31246249 | 0.78 | KCNH2 (1.00) | KCNH2CYP19A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117748-C | Herbicidal 2, 6 -disubstituted pyridines and 2, 4 -disubstituted pyrimidines | AMERICAN CYANAMID CO (US) | 2003-08-13 | — | — | CN | disclosed |
| EP-0723960-B1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | BASF AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| EP-0819690-B1 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | BASF AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6066597-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| US-6008161-A | Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5922726-A | Herbicidal 6-thienyl pyridines and 4-thienyl pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5849758-A | Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5824624-A | HERBICIDES WITH CARRIERS OR SURFACTANTS | AMERICAN CYANAMID COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| US-5747423-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| CN-1175578-A | Herbicidal 2, 6 -disubstituted pyridines and 2, 4 -disubstituted pyrimidines | AMERICAN CYANAMID CO (US) | 1998-03-11 | — | — | CN | disclosed |
| EP-0823431-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1998-02-11 | — | — | EP | disclosed |
| EP-0819690-A2 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | American Cyanamid Company (US) | 1998-01-21 | — | — | EP | disclosed |
| EP-0723960-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1996-07-31 | — | — | EP | disclosed |