Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 2/20 | 0.53 |
| ▸ | CCR5 | P51681 | 2/20 | 0.53 |
| ▸ | CCR8 | P51685 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526361 | 0.95 | KDM4E (0.55) | KCNH2KDM4ELMNACCR1CCR5 | |
| SCHEMBL14732968 | 0.88 | KDM4E (0.63) | KCNH2KDM4ELMNACCR1CCR5 | |
| SCHEMBL7147211 | 0.85 | KCNH2 (0.62) | KCNH2TDP1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL16081689 | 0.84 | KDM4E (0.53) | KCNH2KDM4ELMNACCR1CCR5 | |
| SCHEMBL586654 | 0.81 | KCNH2 (0.49) | KCNH2KDM4ETDP1TP53ALOX15 | |
| SCHEMBL13596181 | 0.81 | KDM4E (0.63) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29483322 | 0.81 | HRH1 (0.63) | KCNH2KDM4ELMNATDP1ALOX15 | |
| SCHEMBL300432 | 0.81 | HRH1 (0.63) | KCNH2KDM4ELMNATDP1ALOX15 | |
| Dipyridyl SCHEMBL28135789 | 0.80 | KDM4E (0.64) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL24581100 | 0.80 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183279-B1 | POLYMERIZATION OF ETHYLENE | DU PONT (US) | 2004-11-24 | — | — | EP | disclosed |
| US-6417364-B1 | NICKEL OR IRON COMPLEXES OF SELECTED NOVEL 2,2-BIPYRIDINE-6-IMINES, OPTIONALLY WITH THE ADDITION OF OTHER COCATALYSTS. THE POLYMERS ARE USEFUL FOR FILMS AND MOLDING RESINS. | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-09 | — | — | US | disclosed |
| US-20020061987-A1 | Polymerization of ethylene | LENGES GERALDINE MARIE (US) | 2002-05-23 | — | — | US | disclosed |
| US-6365690-B1 | CATALYTIC OLEFIN POLYMERIZATION WITH NICKEL IRON COMPLEXES WITH BIPYRIDINE LIGANDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-04-02 | — | — | US | disclosed |