Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985817 | 0.92 | TSHR (0.33) | TSHRALDH1A1L3MBTL1LTB4RLTB4R2 | |
| SCHEMBL4989206 | 0.90 | TSHR (0.37) | TSHRALDH1A1L3MBTL1LMNA | |
| SCHEMBL4982916 | 0.89 | POLB (0.34) | LMNAMAPK1 | |
| SCHEMBL13715791 | 0.88 | — | — | |
| SCHEMBL4980627 | 0.88 | — | — | |
| SCHEMBL4983417 | 0.87 | — | — | |
| SCHEMBL4987724 | 0.87 | MEN1 (0.32) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL4987185 | 0.87 | — | — | |
| SCHEMBL4985199 | 0.86 | ALDH1A1 (0.31) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL4985644 | 0.86 | ALDH1A1 (0.34) | TSHRALDH1A1L3MBTL1CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343827-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | Ciba SC Holding AG (CH) | 2003-09-17 | — | — | EP | claimed |
| WO-2002048205-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | claimed |