Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714765 | 1.00 | PIK3CD (0.43) | PIK3CDSMPD3AKT1IRAK4CNR2 | |
| SCHEMBL716285 | 0.87 | OPRK1 (0.41) | SMPD3AKT1KRASSOS1OPRK1 | |
| SCHEMBL716284 | 0.87 | OPRK1 (0.41) | SMPD3AKT1KRASSOS1OPRK1 | |
| SCHEMBL717891 | 0.87 | LRRK2 (0.39) | PIK3CDCNR2KRASSOS1ALDH1A1 | |
| SCHEMBL717892 | 0.87 | LRRK2 (0.39) | PIK3CDCNR2KRASSOS1ALDH1A1 | |
| SCHEMBL720538 | 0.84 | AKT1 (0.43) | PIK3CDSMPD3AKT1IRAK4CNR2 | |
| SCHEMBL720537 | 0.84 | AKT1 (0.43) | PIK3CDSMPD3AKT1IRAK4CNR2 | |
| SCHEMBL17530839 | 0.84 | OPRK1 (0.43) | SMPD3AKT1OPRK1OPRM1 | |
| SCHEMBL17530762 | 0.83 | OPRK1 (0.40) | SMPD3AKT1KRASSOS1OPRK1 | |
| SCHEMBL716189 | 0.81 | TSHR (0.47) | PIK3CDKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | claimed |
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | disclosed |
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | UCB PHARMA, S.A. (BE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | MAP3K15, PI4KA, MAP3K20 | PIK3CD 12/4885SMPD3 2503/4885AKT1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.