Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.62 |
| ▸ | F7 | P08709 | 10/20 | 0.62 |
| ▸ | F10 | P00742 | 9/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.62 |
| ▸ | CTSV | O60911 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146316 | 0.91 | F7 (0.76) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7149560 | 0.91 | F2 (0.65) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL8140030 | 0.90 | F2 (0.60) | F2PRSS1F7F10PRSS2 | |
| Acetic Acid SCHEMBL8126115 | 0.89 | F7 (0.74) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7150912 | 0.88 | F2 (0.62) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL5881985 | 0.87 | F2 (0.81) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7150803 | 0.86 | F2 (0.82) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7150811 | 0.86 | F2 (0.82) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7150807 | 0.86 | F2 (0.82) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7146577 | 0.85 | F2 (0.70) | F2PRSS1F7F10PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |