Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.62 |
| ▸ | F10 | P00742 | 7/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.62 |
| ▸ | F7 | P08709 | 7/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149560 | 0.93 | F2 (0.65) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7149341 | 0.91 | F7 (0.75) | F2F10PRSS1F7PRSS2 | |
| Acetic Acid SCHEMBL8122452 | 0.90 | F7 (0.73) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7147706 | 0.88 | F2 (0.62) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL5881985 | 0.86 | F2 (0.81) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7147609 | 0.86 | F2 (0.56) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7150807 | 0.86 | F2 (0.82) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7150811 | 0.86 | F2 (0.82) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7150803 | 0.86 | F2 (0.82) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7143722 | 0.84 | F2 (0.70) | F2F10PRSS1F7PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |