SCHEMBL714771

SCHEMBL714771

[NH]c1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
TSHR P16473 3/20 0.48
TP53 P04637 1/20 0.48
CA12 O43570 4/20 0.46
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA6 P23280 4/20 0.46
CA9 Q16790 4/20 0.46
CA4 P22748 3/20 0.46
CA7 P43166 3/20 0.46
CA14 Q9ULX7 3/20 0.46
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
PTGS2 P35354 1/20 0.46
PTPN1 P18031 1/20 0.46
ACE2 Q9BYF1 1/20 0.44
CDC25A P30304 1/20 0.44
CDC25B P30305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343374 0.82 KDM4E (0.52) KDM4ETSHRTP53CA12CA1
SCHEMBL5227394 0.79 MAPT (0.54) KDM4ETSHRTP53CA12CA1
SCHEMBL29899307 0.78 KDM4E (0.69) KDM4ETSHRTP53CA12CA1
SCHEMBL23861 0.78 KDM4E (0.69) KDM4ETSHRTP53CA12CA1
SCHEMBL29350135 0.78 KDM4E (0.69) KDM4ETSHRTP53CA12CA1
SCHEMBL23279 0.78 KDM4E (0.69) KDM4ETSHRTP53CA12CA1
SCHEMBL30163040 0.78 KDM4E (0.69) KDM4ETSHRTP53CA12CA1
SCHEMBL8379342 0.77 CA12 (0.64) KDM4ETSHRTP53CA12CA1
SCHEMBL2702926 0.76 KDM4E (0.67) KDM4ETSHRTP53CA12CA1
SCHEMBL21328422 0.76 KDM4E (0.67) KDM4ETSHRTP53CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
EP-0679173-B1 AZO COMPOUND ZENECA LTD (GB) 1997-12-03 EP claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN disclosed
EP-1865030-B1 DYE-CONTAINING HARDENABLE COMPOSITION, AND COLOR FILTER AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORP (JP) 2013-06-26 EP disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-8124304-B2 Dye-containing curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
US-7709162-B2 Photosensitive composition, color filter, and its production method FUJIFILM CORPORATION (JP) 2010-05-04 US disclosed
US-20090049624-A1 DYE-CONTAINING CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
EP-1865030-A1 DYE-CONTAINING HARDENABLE COMPOSITION, AND COLOR FILTER AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2007-12-12 EP disclosed
US-20060251976-A1 Photosensitive composition, color filter, and its production method FUJI PHOTO FILM CO., LTD. 2006-11-09 US disclosed
US-4881942-A HEATING, FIXING, CONTROLLING PH TO 5.8 TO 8.0 IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-21 US disclosed
EP-0260806-A2 Coloration process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-23 EP disclosed
EP-0084718-B1 TRIPHENDIOXAZINE DYESTUFFS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-16 EP disclosed
US-4472575-A Triphendioxazine dyestuffs IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-09-18 US disclosed
EP-0090114-A2 Reactive dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-10-05 EP disclosed
EP-0084718-A1 Triphendioxazine dyestuffs IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-03 EP disclosed
US-4300902-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-11-17 US disclosed
US-4191687-A Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 US disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 KDM4E 1406/4885TSHR 3565/4885TP53 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.