Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.56 |
| ▸ | F7 | P08709 | 11/20 | 0.56 |
| ▸ | F10 | P00742 | 10/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149296 | 0.96 | BCHE (0.50) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL5882979 | 0.88 | F2 (0.69) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7140881 | 0.85 | F2 (0.71) | F2PRSS1F7F10PRSS2 | |
| Acetic Acid SCHEMBL8127351 | 0.84 | F2 (0.69) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7150796 | 0.83 | F2 (0.55) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7148250 | 0.83 | F2 (0.73) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7169846 | 0.83 | F2 (0.73) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL5882108 | 0.80 | F2 (0.56) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7142032 | 0.80 | F2 (0.62) | F2PRSS1F7F10PRSS2 | |
| Acetic Acid SCHEMBL8127584 | 0.79 | F2 (0.61) | F2PRSS1F7F10PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |