SCHEMBL7147953

SCHEMBL7147953

C/[C]=C(\C)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.46
CES2 O00748 1/20 0.46
AKR1B1 P15121 1/20 0.46
NOS2 P35228 2/20 0.42
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
SLC6A2 P23975 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28460591 0.81 CES1 (0.46) CES1CES2AKR1B1NOS2ALDH1A1
SCHEMBL6802365 0.79 CES1 (0.50) CES1CES2AKR1B1NOS2ALDH1A1
SCHEMBL28056990 0.74 CES1 (0.50) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL57392 0.74 CES1 (0.55) CES1CES2AKR1B1NOS2ALDH1A1
SCHEMBL66721 0.74 CES1 (0.55) CES1CES2AKR1B1NOS2ALDH1A1
SCHEMBL2792481 0.74 CES1 (0.55) CES1CES2AKR1B1NOS2ALDH1A1
Ammonia Solution, Strong SCHEMBL28157017 0.72 CES1 (0.52) CES1CES2AKR1B1NOS2ALDH1A1
SCHEMBL28774551 0.72 CES1 (0.52) CES1CES2AKR1B1NOS2ALDH1A1
Benzene SCHEMBL2333780 0.70 CES1 (0.64) CES1CES2AKR1B1ALDH1A1TSHR
Benzene SCHEMBL7058395 0.70 CES1 (0.64) CES1CES2AKR1B1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343862-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2003-09-17 EP disclosed
WO-2002051972-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2002-07-04 WO disclosed
US-4576753-A MICROBIOCIDES, ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-03-18 US disclosed
US-4472309-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
US-4304718-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-08 US disclosed
US-4264498-A REACTED WITH AN ACID, ITS ACID HALIDE, OR ANHYDRIDE IN THE PRESENCE OF BORON TRIHALIDE AND AN ORGANIC BASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-04-28 US disclosed
US-4181800-A ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-01-01 US disclosed