Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592890 | 0.85 | KDM4E (0.53) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL21843009 | 0.82 | KDM4E (0.53) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL3549969 | 0.82 | KDM4E (0.67) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL5375962 | 0.82 | KDM4E (0.67) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL8307260 | 0.82 | KDM4E (0.67) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL7260873 | 0.81 | KDM4E (0.61) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL9241304 | 0.81 | KDM4E (0.51) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL9073570 | 0.79 | TSHR (0.58) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL9565497 | 0.78 | KDM4E (0.62) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL3957626 | 0.78 | KDM4E (0.62) | KDM4EPOLBTSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156921-A2 | CATALYST LIGANDS, CATALYTIC LIGAND COMPLEXES AND POLYMERIZATION PROCESSES USING SAME | LAVOIE GINO GEORGES (CA) | 2011-12-22 | — | — | WO | disclosed |
| EP-1290048-A2 | COPOLYMERIZATION OF NORBORNENE AND FUNCTIONAL NORBORNENE MONOMERS | EASTMAN CHEMICAL COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096406-A2 | COPOLYMERIZATION OF NORBORNENE AND FUNCTIONAL NORBORNENE MONOMERS | EASTMAN CHEMICAL COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1082362-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000050475-A1 | MIXED OLEFIN POLYMERIZATION CATALYSTS, PROCESSES EMPLOYING SUCH CATALYSTS, AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0973762-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999062968-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1998040374-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |