Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705157 | 0.96 | KDM4E (0.62) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL3549969 | 0.96 | KDM4E (0.67) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL8307260 | 0.96 | KDM4E (0.67) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL13950710 | 0.90 | KDM4E (0.56) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL8352022 | 0.89 | KDM4E (0.59) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL22483593 | 0.89 | KDM4E (0.59) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL10704165 | 0.89 | KDM4E (0.59) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL19437584 | 0.87 | KDM4E (0.53) | KDM4EPOLBTSHRCA1SLC6A2 | |
| SCHEMBL18929793 | 0.87 | KDM4E (0.57) | KDM4EPOLBTSHRCA1CA2 | |
| SCHEMBL13950713 | 0.87 | KDM4E (0.53) | KDM4EPOLBTSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282857-B1 | RADIOACTIVE HALOGEN-LABELED PRECURSOR COMPOUND | INST OF SCIENCE TOKYO (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-20240173305-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | US | disclosed |
| EP-3813946-B1 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-22 | — | — | EP | disclosed |
| CN-117843659-A | Rapamycin analogues and uses thereof | 詹森药业有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-11944605-B2 | Rapamycin analogs and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-02 | — | — | US | disclosed |
| US-20240034721-A1 | RADIOACTIVE HALOGEN LABELING PRECURSOR COMPOUND | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2024-02-01 | — | — | US | disclosed |
| EP-4302827-A2 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN Pharmaceutica NV (BE) | 2024-01-10 | — | — | EP | disclosed |
| EP-4282857-A1 | RADIOACTIVE HALOGEN-LABELED PRECURSOR COMPOUND | Tokyo Institute of Technology (JP) | 2023-11-29 | — | — | EP | disclosed |
| CN-112423843-B | Rapamycin analogues and uses thereof | 詹森药业有限公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20230357776-A1 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-8252778-B2 | Highly fluorinated oils and surfactants and methods of making and using same | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-20090264397-A1 | HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-22 | — | — | US | disclosed |
| US-7226578-B2 | Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis | SHERING AG (DE) | 2007-06-05 | — | — | US | disclosed |
| CN-1910230-A | Fire-retardancy styrene resin composition and its forming product | TEIJIN CHEMICALS LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| US-6916461-B2 | Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis | SCHERING AG (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20050147563-A1 | Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | US | disclosed |
| US-20030232012-A1 | Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis | SCHERING AG (DE) | 2003-12-18 | — | — | US | disclosed |
| US-6468502-B1 | PARAMAGNETIC MACROMOLECULES WITH HIGHER PROTON RELAXIVITY; LOWER DOSAGE AND INCREASED SIGNAL INTENSITY; DETECTING VASCULAR DISEASES; DIFFERENTIATING TISSUE BLOOD SUPPLY LEVELS; DISTINGUISHING MYOCARDIAL INFARCTION FROM ISCHEMIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-6180113-B1 | USED IN TUMOR THERAPY AND INTERVENTIONAL RADIOLOGY | SCHERING AG (DE) | 2001-01-30 | — | — | US | disclosed |
| US-4451509-A | WATERPROOF COATING FOR WOOD | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240034721-A1 | RADIOACTIVE HALOGEN LABELING PRECURSOR COMPOUND | GPR119, SLC5A2, GCKR | KDM4E 3327/4885POLB 2274/4885TSHR 22/4885 |
| US-20050147563-A1 | Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis | FABP1, FLOT1, AFF1 | KDM4E 4553/4885POLB 1811/4885TSHR 892/4885 |
| US-20090264397-A1 | HIGHLY FLUORINATED OILS AND SURFACTANTS AND METHODS OF MAKING AND USING SAME | FLOT1, ABCB4, SGMS1 | KDM4E 4290/4885POLB 2810/4885TSHR 3279/4885 |
| US-11944605-B2 | Rapamycin analogs and uses thereof | RICTOR, MTOR, RPTOR | KDM4E 1565/4885POLB 3464/4885TSHR 3810/4885 |
| US-20240173305-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | RICTOR, MTOR, RPTOR | KDM4E 1565/4885POLB 3464/4885TSHR 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.