Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944352 | 0.89 | IKBKB (0.52) | IKBKBPROKR1SCN9A | |
| SCHEMBL4945716 | 0.79 | IKBKB (0.52) | IKBKBPDE2AMYC | |
| SCHEMBL7170729 | 0.79 | SMARCA2 (0.46) | IKBKBSCN9AALDH1A1HPGD | |
| SCHEMBL14028507 | 0.78 | SMARCA2 (0.49) | IKBKBSCN9AALDH1A1HPGD | |
| SCHEMBL7015775 | 0.77 | IKBKB (0.51) | IKBKBPDE2A | |
| SCHEMBL4942772 | 0.77 | IKBKB (0.56) | IKBKBPDE2ASCN9AMYC | |
| SCHEMBL4942229 | 0.74 | IKBKB (0.53) | IKBKBPDE2APROKR1SCN9AMYC | |
| SCHEMBL4946214 | 0.73 | IKBKB (0.71) | IKBKB | |
| SCHEMBL5718611 | 0.72 | MEN1 (0.52) | IKBKBLMNA | |
| SCHEMBL4939866 | 0.71 | IKBKB (0.50) | IKBKBPDE2ASCN9AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326856-A1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-BETA) INHIBITING ACTIVITY | Bayer Aktiengesellschaft (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002024679-A1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-β) INHIBITING ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | WO | disclosed |