Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215704 | 0.80 | METAP1 (0.42) | METAP1FDPSSMPD1 | |
| SCHEMBL2471725 | 0.80 | METAP1 (0.48) | METAP1FDPSSMPD1 | |
| SCHEMBL27818853 | 0.78 | METAP1 (0.47) | METAP1FDPSSMPD1 | |
| SCHEMBL28667875 | 0.76 | CYP3A4 (0.45) | METAP1FDPSSMPD1 | |
| SCHEMBL20834791 | 0.74 | METAP1 (0.44) | METAP1FDPSSMPD1 | |
| SCHEMBL29790857 | 0.73 | METAP1 (0.42) | METAP1FDPSSMPD1BTN3A1 | |
| SCHEMBL28652294 | 0.73 | METAP1 (0.42) | METAP1FDPSSMPD1 | |
| SCHEMBL2473811 | 0.72 | SMPD1 (0.50) | METAP1FDPSSMPD1 | |
| SCHEMBL20621338 | 0.71 | LPAR3 (0.36) | METAP1FDPSSMPD1 | |
| SCHEMBL27809466 | 0.70 | FDPS (0.44) | METAP1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095671-A1 | METHOD OF DIAGNOSIS AND TREATMENT FOR AFFECTIVE DISORDERS | PHARMACOGENETICS LIMITED (CN) | 2003-11-20 | — | — | WO | disclosed |